THE CORRELATION BETWEEN IMMUNOHISTOCHEMICAL EXPRESSION OF CLUSTER OF DIFFERENTIATION 5 (CD5) AND STROMAL TUMOR INFILTRATING LYMPHOCYTES (STILS) GRADE IN PROSTATE ADENOCARCINOMA

Background: Adenocarcinoma of the prostate is an invasive carcinoma, a neoplasm epithelial cells with secretory cell differentiation. Histomorphology glandular. The are sheets or single neoplasia, basal not seen in this carcinoma. Tumor-Infiltrating Lymphocytes (TILs) lymphocytes that migrate to tumor peritumoral cells. In malignancy, T lymphocyte infiltration can be found, indicating immune response malignancy. cluster Differentiation 5 (CD5) transmembrane receptor plays role regulating function and development Objective: To determine correlation between Immunohistochemical expression Cluster Stromal (sTILs) grade Prostate Adenocarcinoma. Material method: This study was conducted on slides 32 adenocarcinoma patients. Each slide stained hematoxylin eosin (H&E), STILs observed slide. Furthermore, CD5 immunohistochemical staining carried out see analyze whether appearance positive negative. Findings: Among specimens patients, it found 10 mild STILs, 22 moderate no severe (HE) staining, obtained 16 expressions negative expressions. Conclusion: There stromal Lymphocyte (sTILS) adenocarcinoma. .